| 摘要 |
An isomer, enantiomer, diastereoisomer, or tautomer of a compound, represented by formula (I):wherein:A is O, S, NR<1>, or CR1, wherein R1 is defined herein; represents either a single or a double bond;R2 is selected from: H, halogen, R21, OR21, SR21, COOR21, SO2N(R<22>)2, N(R<22>)2, , CON(R<22>)2, NR<22>C(O)R<22> or NR<22>C(O)NR<22> wherein R<21> and each R<22> is defined herein;B is NR<3> or CR<3>, with the proviso that one of A or B is either CR<1> or CR<3>, wherein R<3> is defined herein;K is N or CR<4>, wherein R<4> is defined herein;L is N or CR<5>, wherein R<5> has the same definition as R<4> defined above;M is N or CR<7>, wherein R<7> has the same definition as R<4> defined above;Y<1> is O or S;Z is N(R<6a>)R<6> or OR<6>, wherein R<6a> is H or alkyl or NR<61>R<62> wherein R<61> and R<62> are defined herein;a salt or a derivative thereof, as an inhibitor of HCV NS<5B> polymerase. |
