发明名称 |
2-SUBSTITUTED-1,3-PROPYLIDENEDIPHOSPHONATE DERIVATIVES, THE PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
摘要 |
2-Substituted-1,3-propylidenediphosphonates of formula (I), where A, R1 and R2 are defined in claim 1, are therapeutically active compounds, namely for the treatment of cardiovascular diseases. They can be prepared by reacting phosphonating agents with 1,3- dibromopropanes or ditosylates of 1,3-propanediols substituted in position 2. <IMAGE> (I) . |
申请公布号 |
DE3566545(D1) |
申请公布日期 |
1989.01.05 |
申请号 |
DE19853566545 |
申请日期 |
1985.07.11 |
申请人 |
SYMPHAR S.A. |
发明人 |
NGUYEN MONG, LAN;NIESOR, ERIC;BENTZEN, CRAIG L.;GUYON-GELLIN, YVES;KALATHAKIS, KYRIACOS;PHAN, HIEU TRUNG;ROSSIER, JEAN-ROBERT |
分类号 |
A61K31/665;A61K31/675;A61P9/00;C07F9/38;C07F9/40;C07F9/572;C07F9/58;C07F9/59;C07F9/6509;C07F9/653;C07F9/6533;C07F9/655;C07F9/6561;(IPC1-7):C07F9/38 |
主分类号 |
A61K31/665 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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