AQUEOUS IRON CARBOHYDRATE COMPLEXES, THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM

摘要

A water soluble iron carbohydrate complex obtainable from an aqueous solution of iron (III) salt and an aqueous solution of the oxidation product of one or more maltrodextrins using an aqueous hypochlorite solution at a pH-value within the alkaline range, where, when one maltodextrin is applied, its dextrose equivalent lies between 5 and 20, and when a mixture of several maltodextrins is applied, the dextrose equivalent of the mixture lies between 5 and 20 and the dextrose equivalent of each individual maltodextrin contained in the mixture lies between 2 and 40, a process for its production and a medicament for the treatment and prophylaxis of iron deficiency conditions.

主权项

1. An iron carboxypolymaltose complex of formula:
[FeOx(OH)y(H2O)z]n[{(C6H10O5)(C6H12O7)}]Ik wherein the values for variables x, y, z, n, m, 1 and k are such that said iron carboxypolymaltose complex has an average molecular weight in the range of from about 80 kDa to about 400 kDa and an iron content in the range of from about 24 to about 32% by weight.