RADICAL ACTIVATED CLEAVAGE OF BIOLOGICS AND MICROFLUIDIC DEVICES USING THE SAME

摘要

Disclosed is a cleavage protocol for biological sample characterization using hydroxyl radical activated cleavage in place of traditional enzymatic approaches. The hydroxyl radicals are generated from a semiconductor excited by an energy source. A microfluidic device for the two-dimensional separation of biological samples by hydroxyl radical activated cleavage is also disclosed.