| 发明名称 |
STEREOSELECTIVE RING OPENING REACTIONS |
| 摘要 |
The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile, selected from the group consisting of water, alcohols, carboxylic acids, and thiols, and a racemic or diastereomeric mixture of a cyclic substrate in the presence of a non-racemic, chiral catalyst to effect a kinetic resolution of the cyclic substrate. The present invention also relates to hydrolytic kinetic resolutions of racemic and diastereomeric mixtures of epoxides.
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| 申请公布号 |
WO0009463(A1) |
申请公布日期 |
2000.02.24 |
| 申请号 |
WO1999US18305 |
申请日期 |
1999.08.13 |
| 申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;JACOBSEN, ERIC, N.;TOKUNAGA, MAKOTO;LARROW, JAY, F. |
发明人 |
JACOBSEN, ERIC, N.;TOKUNAGA, MAKOTO;LARROW, JAY, F. |
| 分类号 |
C07D303/04;C07B53/00;C07B57/00;C07B61/00;C07C29/10;C07C31/20;C07C31/28;C07C31/42;C07C33/035;C07C33/26;C07C41/03;C07C41/26;C07C43/03;C07C43/13;C07C43/23;C07C45/64;C07C49/24;C07C67/29;C07C69/30;C07C213/02;C07C247/14;C07C269/06;C07C271/16;C07D203/06;C07D205/00;C07D301/32;C07D303/00;C07D303/08;C07D303/22;C07D303/32;C07D303/36;C07D303/40;C07D303/48;C07D307/00;C07D317/08;C07D317/36;C07F5/00;C07F7/08;C07F7/18;(IPC1-7):C07B53/00 |
主分类号 |
C07D303/04 |
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