发明名称 |
INTEGRIN INTERACTION INHIBITORS FOR THE TREATMENT OF CANCER |
摘要 |
Integrin interaction inhibitors using a beta-turn promoter are described herein. These peptides are useful in treating cancer, such as multiple myeloma, by administering a therapeutically effective amount of the integrin interaction inhibitor. Data show that integrin interaction inhibitors act synergistically or additively interact with anti-proliferative agents such as doxorubicin, SAHA, arsenic trioxide, and etoposide. |
申请公布号 |
US2016257712(A1) |
申请公布日期 |
2016.09.08 |
申请号 |
US201615165687 |
申请日期 |
2016.05.26 |
申请人 |
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. ;UNIVERSITY OF SOUTH FLORIDA |
发明人 |
HAZLEHURST LORI;MCLAUGHLIN MARK;JAIN PRIYESH;DALTON WILLIAM S. |
分类号 |
C07K7/06;A61K45/06;A61K38/08 |
主分类号 |
C07K7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
TAMPA FL US |