发明名称 METHOD FOR TREATING AND PREVENTING THE LOSS OF BONY TISSUE
摘要 FIELD: medicine. ^ SUBSTANCE: the present innovation deals with treating and preventing the loss of bony tissue and/or increased development of bony tissue. For this purpose it is necessary to apply 15-lipoxygenase inhibitors. These molecules could be introduced either individually or in combination with agents that inhibit the resorption of bony tissue or additional agents that regulate calcium resorption out of bony tissue or increase the accumulation of bony tissue. The innovation enables to widen the assortment of medicinal preparations for treating diseases associated with the loss of bony tissue, such as osteoporosis, osteoarthritis, Paget's disease and those of periodontium and, also, the fractures. ^ EFFECT: higher efficiency of therapy. ^ 16 cl, 9 dwg, 7 ex, 5 tbl
申请公布号 RU2319483(C2) 申请公布日期 2008.03.20
申请号 RU20040127131 申请日期 2003.02.03
申请人 F.KHOFFMANN-LJA ROSH AG;DZE GOVERNMENT OF DZE JUNAJTED STEJTS;OREGON KHELS EHND SAJENS JUNIVERSITI 发明人 ALLARD DZHON DEJVID;KLEJN ROBERT FREDERIK;PELTZ GEHRI ALLEN
分类号 A61K31/407;G01N33/50;A61K31/167;A61K31/192;A61K31/404;A61K31/56;A61K31/663;A61K38/18;A61K38/23;A61K38/27;A61K38/30;A61K45/00;A61K45/06;A61P1/02;A61P19/00;A61P19/02;A61P19/08;A61P19/10;C12N9/99;C12N15/09;C12Q1/02;C12Q1/26;C12Q1/68;G01N33/15 主分类号 A61K31/407
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