Method for treating skin lesions with ingenol mebutate

摘要

The invention provides novel methods for topical treatment of skin lesions such as actinic keratosis over treatment areas up to 250 cm2.

主权项

1. A method of treating a subject diagnosed with at least one cancerous or precancerous lesion on a region of skin, said method comprising applying an effective amount of ingenol mebutate to a contiguous treatment area of greater than 25 cm2 located on face, chest or balding scalp for 2 or 3 days, wherein the effective amount of ingenol mebutate is applied in a topical formulation comprising between about 0.018% and about 0.027% ingenol mebutate by weight.