| 摘要 |
PROBLEM TO BE SOLVED: To obtain the subject therapeutic agent useful for prutitus caused by kidney dialysis, bringing about dramatic effects even in the case of an ineffective example by other agents, by using a specific compound known as an antiallergic agent as an active ingredient. SOLUTION: This therapeutic agent comprises (±)- 2[4-(3-ethoxy-2- hydroxypropoxy)phenylcarbamoyl]ethyl}dimethylsulfonium p-toluenesulfonate of the formula as active ingredient. The compound is obtained, for example, by reacting (±)- 2[4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl]ethyl}methyl sulfide with methyl p-toluenesulfonate. Preferably the amount of the compound to be added to each administration unit form is 5-500 mg in an oral agent, 0.1-50 mg in an injection and a percutaneous agent and 5-1,000 mg in a suppository. Preferably the dose of a medicine having the administration form is generally 10-1,000 mg per adult per time.
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