发明名称 TREATMENT OF POST-BARIATRIC HYPOGLYCEMIA WITH GLP-1 ANTAGONISTS
摘要 Treatment of hyperinsulinemic hypoglycemia comprises administration of an effective amount of a glucagon-like peptide-1 receptor antagonist (GLP1RA) alone or in combination with an amylinomimetic agent or any anti-gastric emptying agent. Patients suffering from hyperinsulinemic hypoglycemia after bariatric surgery experience particular benefit, as there is no current method effective for their treatment. Prevention or reduction of acute adverse effects of postprandial hypoglycemia, such as palpitations, tremor, weakness, sweating, confusion, fatigue, blurred vision, seizures, or loss of consciousness, and prevention of chronic adverse effects of hyperinsulinemic hypoglycemia, such as cognitive impairment, can be achieved by treatment with GLP1RA.
申请公布号 WO2016191394(A1) 申请公布日期 2016.12.01
申请号 WO2016US33836 申请日期 2016.05.23
申请人 THE BOT OF THE LELAND STANFORD JUNIOR UNIVERSITY 发明人 MCLAUGHLIN, Tracey L.;CRAIG, Colleen M.
分类号 A61K38/17;A61P3/10 主分类号 A61K38/17
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