发明名称 REGENERATION AND REPAIR OF NERVE BY INDUCTION OF HISTOGENESIS FACTOR
摘要 <P>PROBLEM TO BE SOLVED: To provide a therapeutic treatment method for maintaining neural pathways in a mammal cell; and to provide a composition and a device. <P>SOLUTION: The therapeutic treatment method for maintaining the neural pathways includes enhancing survival of neurons at risk of dying, inducing cellular repair of neurons and the neural pathways, and maintaining their differentiated phenotype. In one embodiment, the invention provides means for stimulating CAM expression in the neurons. The invention also provides means for evaluating the status of nerve tissue, including means for detecting and monitoring neuropathies in a mammal. The method, device and composition include a morphogen-stimulating agent provided to the mammal in a therapeutically effective concentration. <P>COPYRIGHT: (C)2006,JPO&NCIPI
申请公布号 JP2005287512(A) 申请公布日期 2005.10.20
申请号 JP20050108242 申请日期 2005.04.05
申请人 CURIS INC 发明人 RUEGER DAVID C;KUBERASAMPATH THANGAVEL;OPPERMANN HERMANN;OZKAYNAK ENGIN;PANG ROY H L;COHEN CHARLES M
分类号 G01N33/50;A61F2/00;A61K6/00;A61K38/00;A61K38/18;A61K48/00;A61L27/22;A61L27/24;A61P25/00;A61P25/02;A61P25/14;A61P25/16;A61P25/28;A61P25/32;A61P35/00;A61P43/00;C07K14/435;C07K14/47;C07K14/495;C07K14/51;C07K16/22;C12Q1/06;G01N33/53;G01N33/68 主分类号 G01N33/50
代理机构 代理人
主权项
地址