发明名称 |
Chimeric antigen receptor (CAR) with antigen binding domains to the T cell receptor beta constant region |
摘要 |
The present disclosure relates to a chimeric antigen receptor (CAR) which comprises an antigen-binding domain which selectively binds TCR beta constant region 1 (TRBC1) or TRBC2; cells; such a T cells comprising such a CAR; and the use of such cells for the treatment of a T-cell lymphoma or leukaemia in a subject. |
申请公布号 |
AU2015225944(A1) |
申请公布日期 |
2016.09.01 |
申请号 |
AU20150225944 |
申请日期 |
2015.03.05 |
申请人 |
UCL BUSINESS PLC |
发明人 |
PULE, MARTIN;MACIOCIA, PAUL |
分类号 |
C07K14/725;A61K39/395;A61K47/48;C07K16/28 |
主分类号 |
C07K14/725 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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