发明名称 |
AMORPHOUS FORM OF CINNAMIDE COMPOUND |
摘要 |
An amorphous object of (3E)-1-[1(s)-1-(4-fluorophenyl)ethyl]-3-[3-methoxy-4-(4methyl-1H-imidazol-1-yl)benzylidene]piperidine-2-one, which is represented by the formula (1) and has A²-production inhibitory activity. The amorphous object has such satisfactory properties that it has excellent solubility, is stable, does not readily become a crystalline form, and has low hygroscopicity. It is hence suitable for use in pharmaceutical preparations.
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申请公布号 |
EP1808432(A1) |
申请公布日期 |
2007.07.18 |
申请号 |
EP20050805284 |
申请日期 |
2005.10.25 |
申请人 |
EISAI R&D MANAGEMENT CO., LTD. |
发明人 |
KUSHIDA, IKUO;DOI, ERIKO;ITO, KOICHI |
分类号 |
C07D401/06;A61K31/454;A61P25/28 |
主分类号 |
C07D401/06 |
代理机构 |
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代理人 |
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地址 |
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