发明名称 FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS
摘要 The present disclosure relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula I:;;wherein Z1, Z2, Z3, Z4, X, Y, R2, R3 and R4 are as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.
申请公布号 US2016347744(A1) 申请公布日期 2016.12.01
申请号 US201615152231 申请日期 2016.05.11
申请人 Gilead Sciences, Inc. 发明人 Corkey Britton Kenneth;Elzein Elfatih;Graupe Michael;Guerrero Juan;Jiang Robert H.;Kalla Rao V.;Koltun Dmitry;Li Xiaofen;Martinez Ruben;Parkhill Eric Q.;Perry Thao;Venkataramani Chandrasekar;Zablocki Jeff
分类号 C07D413/06;A61K31/553 主分类号 C07D413/06
代理机构 代理人
主权项
地址 Foster City CA US