发明名称 |
PROCESS FOR MAKING STERILE ARIPIPRAZOLE OF DESIRED MEAN PARTICLE SIZE |
摘要 |
<p>A process is provided for making sterile aripiprazole having an average particle size less than 100 microns but preferably greater than 25 microns employing an impinging jet crystallization procedure. The resulting bulk aripiprazole of desired particle size may be used to form a sterile freeze-dried aripiprazole formulation, which upon constitution with water and intramuscular injection releases aripiprazole over a period of at least about one week and up to about eight weeks.</p> |
申请公布号 |
IL175008(D0) |
申请公布日期 |
2006.08.20 |
申请号 |
IL20060175008 |
申请日期 |
2006.04.20 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
|
分类号 |
B01D9/00;C07D;C07D215/22;C07D215/227 |
主分类号 |
B01D9/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|