| 发明名称 |
TNF-DERIVED PEPTIDES FOR USE IN TREATING OEDEMA |
| 摘要 |
The present invention relates to the finding that peptides derived from a specific domain of tumor necrosis factor-alpha (TNF-.alpha.) can efficiently be used to treat oedema. More specifically, the present invention relates to the usage of peptides derived from the region of human TNF-.alpha. from Ser1 00 to Glu116 to treat pulmonary oedema. Moreover, the present invention concern s a circularized peptide having amino acid sequence CGQRETPEGAEAKPWYC which is very efficient in inducing oedema resorption.
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| 申请公布号 |
CA2334941(A1) |
申请公布日期 |
2000.02.24 |
| 申请号 |
CA19992334941 |
申请日期 |
1999.08.10 |
| 申请人 |
INNOGENETICS N.V. |
发明人 |
FRANSEN, LUCIE;BLOC, ALAIN;PUGIN, JEROME;DE BAETSELIER, PATRICK;LUCAS, RUDOLF |
| 分类号 |
A61K38/00;A61K;A61K38/19;A61P;A61P3/00;A61P7/10;A61P11/00;A61P43/00;C07K;C07K7/06;C07K7/08;C07K14/525;(IPC1-7):A61K38/19 |
主分类号 |
A61K38/00 |
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