DIPEPTIDE INHIBITING ANGIOGENESIS IN OPHTHALMOPATHOLOGY

摘要

The invention refers to medicine and concerns the ophthalmologic application of dipeptide L-lysyl-L-glutamic acid (L-Lys-L-Glu) as a preparation inhibiting neovascularisation in ocular diseases. There is proposed the application od L-Lys-L-Glu dipeptide or one of its salts as a substance capable of angiogenesis inhibition in ophthalmopathology. There is proposed a pharmaceutical preparation for parenteral administration including the claimed dipeptide or one of its salts in the amount, which is effective for the prevention of and/or treatment for ophthalmopathology requiring angiogenesis inhibition and which does not exceed 10 mu g in 1 m1 of a pharmaceutically admissible carrier. There is proposed a method of ophthalmopathology treatment consisting in the preventive and/or therapeutic administration to a patient of an effective amount of the claimed pharmaceutical preparation for a period required to attain a therapeutic effect with regard to the character of the pathology development. The claimed pharmaceutical preparation is active when administered in the does range of 0.1-100 mu g/kg of the body weight.