发明名称 |
Reaction-based fluorescent probes for sulfane sulfur and the application in bioimaging |
摘要 |
Reaction-based fluorescent probes are provided which detect, for example, biologically important sulfane sulfur species (persulfide, polysulfide, and elemental sulfur) in, for example, complex and living systems. The probes are high in selectivity and sensitivity to sulfane sulfurs. Moreover, probes are suitable for bioimaging sulfane sulfurs in living cells. |
申请公布号 |
US9494592(B2) |
申请公布日期 |
2016.11.15 |
申请号 |
US201414250481 |
申请日期 |
2014.04.11 |
申请人 |
Washington State University |
发明人 |
Xian Ming;Chen Wei |
分类号 |
A61B5/00;A61B8/00;A61B10/00;G01N33/58;C07D493/10;C07D311/16;A61K49/00 |
主分类号 |
A61B5/00 |
代理机构 |
Whitham, Curtis & Cook, P.C. |
代理人 |
Whitham, Curtis & Cook, P.C. |
主权项 |
1. A fluorescent probe comprising:
a linker; a nucleophile; a fluorophore; said fluorescent probe having the formula wherein the fluorophore is |
地址 |
Pullman WA US |