| 发明名称 |
TELOMERASE ENCODING DNA VACCINE |
| 摘要 |
The invention provides a nucleic acid construct comprising a sequence that encodes a human telomerase reverse transcriptase (hTERT) protein which is devoid of telomerase catalytic activity and of a nucleolar localization signal. The construct is useful triggering an immune response in a subject, against cells that overexpress telomerase, preferably dysplasia cells or tumor cells. |
| 申请公布号 |
US2016263204(A1) |
申请公布日期 |
2016.09.15 |
| 申请号 |
US201415032966 |
申请日期 |
2014.10.28 |
| 申请人 |
INVECTYS |
发明人 |
Langlade Demoyen Pierre;Wain-Hobson Simon;Huet Thierry;Liard Christelle;Pliquet Elodie |
| 分类号 |
A61K39/00;C12N9/12 |
主分类号 |
A61K39/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A nucleic acid construct comprising a sequence that encodes a human telomerase reverse transcriptase (hTERT) protein which is devoid of telomerase catalytic activity and of a nucleolar localization signal. |
| 地址 |
Paris FR |
