摘要 |
Compounds of formula (I): wherein X, Y, R1 and R3-R11 are as herein defined, and salts thereof are PAD4 inhibitors and may be useful in the treatment of various disorders, for example rheumatoid arthritis, vasculitis, systemic lupus erythematosus, ulcerative colitis, cancer, cystic fibrosis, asthma, cutaneous lupus erythematosis, and psoriasis. |
申请人 |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED |
发明人 |
AMANS, Dominique;ATKINSON, Stephen, John;BARKER, Michael, David;CAMPBELL, Matthew;DIALLO, Hawa;DOUAULT, Clement;GARTON, Neil, Stuart;LIDDLE, John;RENAUX, Jessica, Fanny;SHEPPARD, Robert, John;WALKER, Ann, Louise;WELLAWAY, Christopher, Roland;WILSON, David, Matthew |