发明名称 |
(6S,9aS)-N-BENZYL-6-[(4-HYDROXYPHENYL)METHYL]-4,7-DIOXO-8-({6-[3-(PIPERAZINE-1-YL)AZETIDINE-1-YL]PYRIDINE-2-YL}METHYL)-2-(PROP-2-EN-1-YL)-OCTAHYDRO-1H-PYRAZINO[2,1-c][1,2,4]TRIAZINE-1-CARBOXAMIDE COMPOUND |
摘要 |
A compound represented by formula (1) or pharmaceutically acceptable salt thereof: wherein R1 is a C1-6 alkyl group; R2 and R3 are the same or different from each other and each is a hydrogen atom or a C1-6 alkyl group; X2, X3 and X4 are the same or different from each other and each is a hydrogen atom or a halogen atom; and X5 is a hydrogen atom or —P(═O)(OH)2 has a Wnt Pathway modulating activity. |
申请公布号 |
SG11201604496Y(A) |
申请公布日期 |
2016.07.28 |
申请号 |
SG11201604496Y |
申请日期 |
2014.12.22 |
申请人 |
EISAI R&D MANAGEMENT CO., LTD.;PRISM PHARMA CO., LTD. |
发明人 |
INOUE SATOSHI;YAMAMOTO YUJI;ISO KENTARO |
分类号 |
C07D487/04;A61K31/53;A61K31/661;A61P11/00;A61P35/00;A61P43/00;C07F9/09 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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