发明名称 (6S,9aS)-N-BENZYL-6-[(4-HYDROXYPHENYL)METHYL]-4,7-DIOXO-8-({6-[3-(PIPERAZINE-1-YL)AZETIDINE-1-YL]PYRIDINE-2-YL}METHYL)-2-(PROP-2-EN-1-YL)-OCTAHYDRO-1H-PYRAZINO[2,1-c][1,2,4]TRIAZINE-1-CARBOXAMIDE COMPOUND
摘要 A compound represented by formula (1) or pharmaceutically acceptable salt thereof: wherein R1 is a C1-6 alkyl group; R2 and R3 are the same or different from each other and each is a hydrogen atom or a C1-6 alkyl group; X2, X3 and X4 are the same or different from each other and each is a hydrogen atom or a halogen atom; and X5 is a hydrogen atom or —P(═O)(OH)2 has a Wnt Pathway modulating activity.
申请公布号 SG11201604496Y(A) 申请公布日期 2016.07.28
申请号 SG11201604496Y 申请日期 2014.12.22
申请人 EISAI R&D MANAGEMENT CO., LTD.;PRISM PHARMA CO., LTD. 发明人 INOUE SATOSHI;YAMAMOTO YUJI;ISO KENTARO
分类号 C07D487/04;A61K31/53;A61K31/661;A61P11/00;A61P35/00;A61P43/00;C07F9/09 主分类号 C07D487/04
代理机构 代理人
主权项
地址