发明名称 TOTAL SYNTHESIS OF PLADIENOLIDE B AND PLADIENOLIDE D
摘要 <p>Disclosed is a process for production of a compound represented by the formula (11): [wherein P 1 represents a hydrogen atom or a protective group for a hydroxyl group; P 7 represents a hydrogen atom or a protective group for a hydroxyl group; P 8 represents a hydrogen atom, an acetyl group or a protective group for a hydroxyl group and P 9 represents a hydrogen atom or a protective group for a hydroxyl group, or P 8 and P 9 may together form a group represented by the formula: (where R 5 represetns a phenyl group which may have a halogen atom; and R 1 represetns a hydrogen atom or a hydroxyl group)]. The process comprises the step of reacting a compound represented by the formula (12): (wherein P 7 and R 1 are as defined above) with a compound represented by the formula (13): (wherein P 1 , P 8 , P 9 and R 5 are as defined above) in the presence of a catalyst.</p>
申请公布号 IL190233(D0) 申请公布日期 2008.11.03
申请号 IL20080190233 申请日期 2008.03.17
申请人 EISAI R& D MANAGEMENT CO., LTD. 发明人
分类号 C07D 主分类号 C07D
代理机构 代理人
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