发明名称 |
PYRROLO[2,3-d]PYRIMIDINE COMPOUNDS |
摘要 |
A compound of formula (I) wherein R<1>, R<2> and R<3> are as defined above, which are inhibitors of the enzyme protein kinases such as Janus Kinase 3 and as such are useful therapy as immunosuppressive agents for organ transplants, xeno transplantation, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis, Type I diabetes and complications from diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid disorders, ulcerative colitis, Crohn's disease, Alzheimer's disease, Leukemia and other autoimmune diseases.
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申请公布号 |
WO0142246(A3) |
申请公布日期 |
2001.11.22 |
申请号 |
WO2000IB01742 |
申请日期 |
2000.11.23 |
申请人 |
PFIZER PRODUCTS INC.;BLUMENKOPF, TODD, ANDREW;FLANAGAN, MARK, EDWARD;MUNCHHOF, MICHAEL, JOHN |
发明人 |
BLUMENKOPF, TODD, ANDREW;FLANAGAN, MARK, EDWARD;MUNCHHOF, MICHAEL, JOHN |
分类号 |
A61K31/365;A61K31/445;A61K31/519;A61K38/13;A61K45/06;A61P1/00;A61P1/04;A61P3/10;A61P11/06;A61P17/00;A61P17/06;A61P25/28;A61P29/00;A61P35/00;A61P35/02;A61P37/00;A61P37/06;A61P43/00;C07D487/02;C07D487/04;(IPC1-7):C07D487/04 |
主分类号 |
A61K31/365 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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