| 摘要 |
<P>PROBLEM TO BE SOLVED: To decode the length of a long base in a DNA sequencer using an FET sensor. <P>SOLUTION: Target DNA is immobilized on the surfaces of spherical particulates 212, 242 and 250 and the particulates are arranged in the vicinity of the metal electrodes 209, 241 and 248 having spherical surfaces which are electrically connected to the conductive wires 208, 238 and 247 of the FET sensor and can be partly brought into contact with the particulates while a change in the interfacial potential accomponied by the extension reaction of DNA molecules 232, 243 and 251, wherein target DNA and probe DNA are hybridized, is detected by the FET sensor. <P>COPYRIGHT: (C)2009,JPO&INPIT |
