| 发明名称 |
MUTATED E. COLI HEAT-LABILE ENTEROTOXIN |
| 摘要 |
This invention relates to a mutant E. coli heat-labile enterotoxin (LT) subunit A that can be used as an adjuvant. This subunit A mutant contains an amino acid substitution at a position corresponding to position 61 of a wild-type LT. An LT containing this mutated subunit A exhibits reduced toxicity compared to its wild type counterpart. |
| 申请公布号 |
CA2685495(C) |
申请公布日期 |
2016.10.04 |
| 申请号 |
CA20072685495 |
申请日期 |
2007.08.13 |
| 申请人 |
DEVELOPMENT CENTER FOR BIOTECHNOLOGY |
发明人 |
HSU, YU-SHEN;LIN, YOUNG-SUN;YUAN, TA-TUNG |
| 分类号 |
C12N15/31;A61K39/385;A61K39/39;A61P37/04;C07K14/245;C12N9/10 |
主分类号 |
C12N15/31 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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