发明名称 HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
摘要 <p>Provided herein are Aminopurine Compounds having the following structure: wherein R 1 , R 2 and and R 3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.</p>
申请公布号 SI1838710(T1) 申请公布日期 2009.10.31
申请号 SI20060030365T 申请日期 2006.01.13
申请人 SIGNAL PHARMACEUTICALS LLC;PHARMACOPEIA, LLC 发明人 ALBERS RONALD;AYALA LETICIA;CLAREEN STEVEN S.;DELGADO MEDEROS MARIA M.;HILGRAF ROBERT;HEDGE SAYEE;HUGHES KEVIN;KOIS ADAM;PLANTEVIN-KRENITSKY VERONIQUE;MCCARRICK MEG;NADOLNY LISA;PALANKI MOORTHY;SAHASRABUDHE KIRAN;SAPIENZA JOHN;SATOH YOSHITAKA;SLOSS MARIAN;SUDBECK ELISE;WRIGHT JONATHAN;COLE ANDREW G.;HENDERSON IAN
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