发明名称 METHOD FOR EXTRACTING OLEAGINOUS SUBSTANCE FROM GANODERMA LUCIDUM SPORE
摘要 PROBLEM TO BE SOLVED: To provide a method for extraction by which an oleaginous substance in Ganoderma lucidum spores can be obtained in high yield in a good state. SOLUTION: This method for extracting the oleaginous substance from germination- activated Ganoderma spores or nongermination-activated Gaderma spores comprises (1) breaking the sporoderm with a mechanical means and (2) extracting the oleaginous substance from the sporoderm-broken spores using a method for superctitical fluid- carbon dioxide (SCF-CO2 ) extraction. The preferred supercritical conditions are 5-60 MPa supercritical pressure, 32-85 deg.C supercritical temperature and 5-80 kg/h flow capacity rate. The preferred SCF-CO2 extraction time is 0.5-6 h. The method for activating germination of the Ganoderma spores is carried out by (1) culturing the spores in a nutritional solution and inducing the germination and then (2) placing the spores in a sufficiently ventilated culture box at a constant temperature and humidity and activating the spores. According to the method for extraction, the oleaginous substance in an amount of about 37% based on the spore weight is obtained and the resultant oleaginous substance is transparent and has a fragrance unique to the Ganoderma spores. There is no trace of deposit, solvent residue or oxidation in the oleaginous substance.
申请公布号 JP2002275190(A) 申请公布日期 2002.09.25
申请号 JP20010233759 申请日期 2001.08.01
申请人 PETER CHEE-KEUNG CHUNG 发明人 LIU XIN;HUANG XIAO-NI;PETER CHEE-KEUNG CHUNG
分类号 C12P1/02;A61K36/06;A61K36/074;A61P31/12;A61P31/18;A61P35/00;A61P37/02;B01D11/02;C07G99/00;C12N1/14 主分类号 C12P1/02
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