发明名称 |
COMPOSITION AND METHODS FOR EVALUATING AN ORGANISM'S RESPONSE TO ALCOHOL |
摘要 |
This invention pertains to the identification of genes whose expression levels are altered by chronic exposure of a cell, tissue, or organism to one or more drugs of abuse (e.g. alcohol, stimulants, opiates, etc.). In one embodiment, this invention provides a method of monitoring the response of a cell to a drug of abuse. The method involves contacting the cell with the drug of abuse; providing a biological sample comprising the cell; and detecting, in the sample, the expression of one or more genes or ESTs identified herein, where a difference between the expression of one or more of said genes of ESTs in said sample and one or more of said genes or ESTs in a biological sample not contacted with said drug of abuse indicates a response of the cell to the drug of abuse.
|
申请公布号 |
WO9967267(A1) |
申请公布日期 |
1999.12.29 |
申请号 |
WO1999US13839 |
申请日期 |
1999.06.22 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;MILES, MICHAEL, F.;LAI, CHAO-QIANG;LOCKHART, DAVID, J. |
发明人 |
MILES, MICHAEL, F.;LAI, CHAO-QIANG;LOCKHART, DAVID, J. |
分类号 |
C12Q1/68;(IPC1-7):C07H21/00 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|