Human HisRS genes are identified as modulators of the SREPB pathway and thus are therapeutic for disorders associated with the SREBP pathway. Methods for identifying modulators of HisRS, comprising screening for agents that modulate the activity of HisRS are provided.
申请公布号
WO02055663(A2)
申请公布日期
2002.07.18
申请号
WO2002US01045
申请日期
2002.01.11
申请人
EXELIXIS, INC.;SEIDEL-DUGAN, CYNTHIA;KADYK, LISA, C.;MAPA, PHELIPA, A.
发明人
SEIDEL-DUGAN, CYNTHIA;KADYK, LISA, C.;MAPA, PHELIPA, A.