发明名称 |
TRKA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF. |
摘要 |
The present invention is directed to six membered heteroaryl benzamide compounds of formula (I), which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA. |
申请公布号 |
MX2016012480(A) |
申请公布日期 |
2016.12.20 |
申请号 |
MX20160012480 |
申请日期 |
2015.03.23 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
BAO, Jianming;FRALEY, Mark E.;LI, Chun Sing;WOOD, Harold B.;CHEN, Yi-Heng;STUMP, Craig A.;LIU, Ping;MERCER, Swati P.;MENG, Dongfang;Kerim BABAOGLU;Helen MITCHELL;Andrew J. COOKE;Kathy SCHIRRIPA;Jane WU;Xu- Fang ZHANG;Casey C. MCCOMAS;Melody MCWHERTER;Qinghua MAO;Zhiqi QI |
分类号 |
A61K31/166;C07D471/04 |
主分类号 |
A61K31/166 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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