发明名称 |
ANTIKÖRPER GEGEN EIN EPITOP AUF AGR2, ASSAYS UND HYBRIDOME |
摘要 |
<p>Provided is a monoclonal antibody, or an antigen binding fragment thereof, which binds specifically to an epitope within the sequence KPGAKKDTKDSRPKL (Sequence ID No. 2) of AGR2. Such monoclonal antibodies are of prognostic and diagnostic utility in the investigation of cancer, particularly metastatic cancer. The antibodies described may also be used in prognosis or diagnosis of inflammatory diseases. Also provided are kits and solid supports comprising such antibodies, as well as the therapeutic use of antibodies of the invention.</p> |
申请公布号 |
AT474857(T) |
申请公布日期 |
2010.08.15 |
申请号 |
AT20070789322T |
申请日期 |
2007.08.28 |
申请人 |
THE UNIVERSITY OF LIVERPOOL |
发明人 |
BARRACLOUGH, ROGER;BARRACLOUGH, DONG;RUDLAND, PHILIP |
分类号 |
C07K16/30;A61K39/395;A61P35/00;A61P37/00;G01N33/574;G01N33/577 |
主分类号 |
C07K16/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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