发明名称 Wnt/b-catenin inhibitors and methods of use
摘要 This disclosure relates to inhibitors of the Wni pathway, and compositions comprising the same, as well as to their use in the treatment of disorders characterized by the activation of Writ pathway signaling (e.g., cancer), as well as to the modulation of cellular events mediated by VVnt pathway signaling.
申请公布号 US9469606(B2) 申请公布日期 2016.10.18
申请号 US201214353667 申请日期 2012.10.25
申请人 The General Hospital Corporation 发明人 Lee Sam W.;Mandinova Anna I.
分类号 C07C317/48;C07C317/32;A61K31/18 主分类号 C07C317/48
代理机构 Fish & Richardson P.C. 代理人 Fish & Richardson P.C.
主权项 1. A method of treating cancer in a patient, the method comprising administering to the patient a therapeutically effective amount of a compound selected from the group consisting of:or a pharmaceutically acceptable salt thereof.
地址 Boston MA US