发明名称 |
Pharmaceutical composition for oral use with angiotensin-II-antagonistic activity and method of preparing it |
摘要 |
<p>A pharmaceutical composition for oral use comprising an effective amount of a compound of the formula (I) having antagonistic action to angiotensin II
(wherein the ring W is an optionally substituted N-containing heterocyclic residue; R 3 is a group capable of forming an anion or a group convertible thereinto; X is a direct bond or a spacer having an atomic length of two or less between the phenylene group and the phenyl group; and n is an integer of 1 or 2) and an oleaginous substance having a lower melting point, and
a method for preparing a pharmaceutical composition for oral use comprising an effective amount of a compound of the formula (I) and an oily substance having a lower melting point, which comprises admixing the compound of the formula (I) with an oily substance having a lower melting point and then subjecting the mixture to molding.</p> |
申请公布号 |
EP1468683(A2) |
申请公布日期 |
2004.10.20 |
申请号 |
EP20040013762 |
申请日期 |
1992.11.19 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES LTD |
发明人 |
MAKINO TADASHI;MIZUKAMI YOSHIO;KIKUTA JUN-ICHI |
分类号 |
A61K31/415;A61K9/00;A61K9/20;A61K31/41;A61K31/4184;A61K31/435;A61K31/495;A61K31/53;(IPC1-7):A61K31/415 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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