| 发明名称 |
HETEROCYCLIC MODULATORS OF TGR5 |
| 摘要 |
Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of modulation of TGR5 activity in a human or animal subject are also provided for the treatment diseases mediated by TGR5.
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| 申请公布号 |
US2009105124(A1) |
申请公布日期 |
2009.04.23 |
| 申请号 |
US20080193579 |
申请日期 |
2008.08.18 |
| 申请人 |
KALYPSYS, INC. |
发明人 |
SMITH NICHOLAS D.;PAYNE JOSEPH E.;HOFFMAN TIMOTHY Z.;BONNEFOUS CELINE;PINKERTON ANOTHONY B.;SIEGEL DANA L. |
| 分类号 |
A61K38/28;A61K31/4985;A61K31/5025;A61P3/00;A61P3/10;A61P19/02;A61P29/00;C07D471/04;C07D475/02 |
主分类号 |
A61K38/28 |
| 代理机构 |
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