SYNBIOTIC TO IMPROVE GUT MICROBIOTA IN INFANTS DELIVERED BY CAESAREAN SECTION

摘要

The use of a probiotic strain of Lactobacillus rhamnosus and an oligosaccharide mixture which comprises 5-70 wt% of at least one N-acetylated oligosaccharide selected from the group comprising GalNAcαl,3Gal&bgr;1,4Glc and Gal&bgr;l,6GalNAcαl,3Gal&bgr;1,4Glc, 20-90 wt% of at least one neutral oligosaccharide selected from the group comprising Gal&bgr;l,6Gal, Gal&bgr;l,6Gal&bgr;1,4Glc Gaipi,6Gaipi,6Glc, Gal&bgr;4,3Gal&bgr;1,3Glc, Gal&bgr; 1,3Galp l,4GIc, Gal&bgr;l,6Gaip l,6Gal&bgr; l,4GIc, Gal&bgr; l,6Gal&bgr; l,3Gal&bgr; l,4GIc Galp4,3Gal&bgr;l,6Gal&bgr;1,4Glc and Gal&bgr; l,3Gal&bgr;1,3Gal&bgr;1, 4GIc and 5-50 wt% of at least one sialylated oligosaccharide selected from the group comprising NeuAcα2,3Ga&bgr;1,4Glc and NeuAcα2,6Ga&bgr;1,4Glc in the manufacture of a medicament or therapeutic nutritional composition for promoting the development of an early bifidogenic intestinal microbiota in infants delivered by caesarean section is disclosed.