| 发明名称 |
Anti-IL-22RA antibodies and binding partners and methods of using in inflammation |
| 摘要 |
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-22, IL-20, or both IL-20 and IL-22 polypeptide molecules. IL-20 and IL-22 are cytokines that are involved in inflammatory processes and human disease. IL-22RA (zcytor11) is a common receptor for IL-20 and IL-22. The present invention includes anti-IL-22RA antibodies and binding partners, as well as methods for antagonizing IL-22 or both IL-20 and IL-22 using such antibodies and binding partners.
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| 申请公布号 |
US8163286(B2) |
申请公布日期 |
2012.04.24 |
| 申请号 |
US20090580987 |
申请日期 |
2009.10.16 |
| 申请人 |
XU WENFENG;KINDSVOGEL WAYNE;CHANDRASEKHER YASMIN A.;DILLON STACEY R.;LEHNER JOYCE M.;SIADAK ANTHONY W.;SIVAKUMAR PALLAVUR V.;MOORE MARGARET D.;ZYMOGENETICS, INC. |
发明人 |
XU WENFENG;KINDSVOGEL WAYNE;CHANDRASEKHER YASMIN A.;DILLON STACEY R.;LEHNER JOYCE M.;SIADAK ANTHONY W.;SIVAKUMAR PALLAVUR V.;MOORE MARGARET D. |
| 分类号 |
A61K39/395;A61K39/00;C07K14/54;C07K14/715;C07K16/18;C07K16/24;C07K16/28 |
主分类号 |
A61K39/395 |
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