COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT

摘要

Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the antimicrobial agent, methods of treatment of an infection, methods of treatment using compositions or pharmaceutical compositions, and the like.

主权项

1. A composition, comprising an antimicrobial agent having the following structure:wherein R1 is selected from the group consisting of: H, alkyl, aryl, (CH2)nCOOH with n=1-6, OH, and O-alkyl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted; wherein R2 is selected from the group consisting of: H, alkyl, aryl, (CH2)nCOOH with n=1-6, OH, and O-alkyl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted; wherein R3 is selected from the group consisting of: H, alkyl, aryl, and COOH, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted; wherein R4 is selected from the group consisting of:wherein Y is selected from the group consisting of: H, OH, NO2, COOH, halogen, alkyl, and O-alkly, where each alkyl group is independently optionally substituted or unsubstituted, wherein R6 is selected from the group consisting of: alkyl, O-alkyl, O-aryl, and aryl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted; and wherein R7 is selected from the group consisting of: alkyl, O-alkyl, O-aryl, and aryl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted.