发明名称 |
PROSTATE-SPECIFIC MEMBRANE ANTIGEN |
摘要 |
This invention provides for an isolated mammalian nucleic acid molecule encoding a mammalian prostate-specific membrane antigen. This invention provides for nucleic acid probes which specifically hybridize with the nucleic acid molecule encoding said antigen. This invention provides for a method of detecting hematogenous micrometastic tumor cells of a subject performing the polymerase chain reaction (PCR) on samples of the subjet using primers of said antigen. This invention provides for methods to identify ligands which bind to said antigen. This invention provides for the prevention and/or treatment of prostate tumor growth.
|
申请公布号 |
CA2147499(A1) |
申请公布日期 |
1994.05.11 |
申请号 |
CA19932147499 |
申请日期 |
1993.11.05 |
申请人 |
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH |
发明人 |
ISRAELI, RON S.;HESTON, WARREN D. W.;FAIR, WILLIAM R. |
分类号 |
A01K67/027;A61K9/00;A61K38/00;A61K39/00;A61K39/395;A61K48/00;A61K51/00;A61P35/00;C07H21/04;C07K7/06;C07K7/08;C07K14/705;C07K14/82;C07K16/30;C07K16/32;C07K19/00;C12N5/10;C12N15/09;C12N15/12;C12P21/02;C12P21/08;C12Q1/68;G01N33/53;G01N33/68;(IPC1-7):C12N15/12;A61K51/10;C07K1/22;C07K16/28;A61K47/48;G01N33/566;G01N33/574;A61K31/70 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|