发明名称 |
Method for manufacturing an active component of a medicine or diagnosis agent in MDCK cell suspension culture |
摘要 |
<p>Preparation of an active component (I) of a therapeutic or diagnostic agent by: (i) infecting Mandine-Darby canine kidney (MDCK) cells with a virus; and (ii) culturing the cells in suspension culture on a large scale (i.e. culture volume at least 30 l), so that viral replication occurs. An independent claim is also included for preparation of a therapeutic or diagnostic composition by formulating (I) prepared by the new method with adjuvants, auxiliaries, buffers, diluents or carriers. ACTIVITY : Virucide. No biological data given. MECHANISM OF ACTION : Vaccine.</p> |
申请公布号 |
EP2011862(A1) |
申请公布日期 |
2009.01.07 |
申请号 |
EP20080018057 |
申请日期 |
2002.09.11 |
申请人 |
NOVARTIS VACCINES AND DIAGNOSTICS GMBH & CO. KG |
发明人 |
GREGERSEN, JENS-PETER;VORLOP, JUERGEN;FRECH, CHRISTIAN;LUEBBEN, HOLGER |
分类号 |
C12N5/06;C12P21/02;A61K39/00;A61K39/12;A61K39/39;A61K48/00;A61P31/12;C12N5/10;C12N7/00;C12N7/02;C12N15/867 |
主分类号 |
C12N5/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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