发明名称 Method for manufacturing an active component of a medicine or diagnosis agent in MDCK cell suspension culture
摘要 <p>Preparation of an active component (I) of a therapeutic or diagnostic agent by: (i) infecting Mandine-Darby canine kidney (MDCK) cells with a virus; and (ii) culturing the cells in suspension culture on a large scale (i.e. culture volume at least 30 l), so that viral replication occurs. An independent claim is also included for preparation of a therapeutic or diagnostic composition by formulating (I) prepared by the new method with adjuvants, auxiliaries, buffers, diluents or carriers. ACTIVITY : Virucide. No biological data given. MECHANISM OF ACTION : Vaccine.</p>
申请公布号 EP2011862(A1) 申请公布日期 2009.01.07
申请号 EP20080018057 申请日期 2002.09.11
申请人 NOVARTIS VACCINES AND DIAGNOSTICS GMBH & CO. KG 发明人 GREGERSEN, JENS-PETER;VORLOP, JUERGEN;FRECH, CHRISTIAN;LUEBBEN, HOLGER
分类号 C12N5/06;C12P21/02;A61K39/00;A61K39/12;A61K39/39;A61K48/00;A61P31/12;C12N5/10;C12N7/00;C12N7/02;C12N15/867 主分类号 C12N5/06
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