发明名称 |
METHOD FOR DETERMINATION OF PROGNOSIS OF PROSTATE CANCER, AND DIAGNOSTIC AGENT FOR USE IN THE METHOD |
摘要 |
A method for determining probability that prostate cancer will metastasize, as well as a diagnostic reagent used therefor is disclosed. It was discovered that the percentage that NF-ºB-p65/RelA has the 254th amino acid threonine which is phosphorylated is significantly higher in the prostate cancer cells in the cases where the bone metastasis was observed than in the cases where bone metastasis was not observed. Thus, the method for determining probability that prostate cancer will metastasize comprises measuring human NF-ºB-p65/RelA in which 254th amino acid threonine is phosphorylated, which human NF-ºB-p65/RelA is contained in a prostate tissue separated from human.
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申请公布号 |
EP2012128(A1) |
申请公布日期 |
2009.01.07 |
申请号 |
EP20070740484 |
申请日期 |
2007.03.30 |
申请人 |
YOKOHAMA CITY UNIVERSITY |
发明人 |
RYO, AKIHIDE;AOKI, ICHIRO;SASAKI, TAKESHI |
分类号 |
G01N33/574 |
主分类号 |
G01N33/574 |
代理机构 |
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主权项 |
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地址 |
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