摘要 |
Highly expandable materials have been developed for filling an aneurysm sac and for sealing of endoluminal devices vessel walls. The expandable materials may be hydrogels comprising a polymer selected from poly(acrylic acid), poly(acrylamide), and poly(methacrylic acid), copolymers and blends of each, crosslinked with a di- or polyvalent crosslinking agent. The expandable materials have appropriate chemical and physical properties to withstand radiation, sterilization, or storage in sterilizing solution, without loss of expandable characteristics. The expandable materials may contain protectants, prophylactic, diagnostic, therapeutic, or imaging agents. The expandable materials form a seal that actively conforms to vascular anatomy sealing any leaks that may occur after device implantation. In one embodiment, the technology is used to prevent leaks associated with abdominal aortic aneurysm (AAA) repair, especially for complex AAA repair. |
申请人 |
ENDOLUMINAL SCIENCES PTY LTD |
发明人 |
MITRA, ASHISH;SOMMER-KNUDSEN, JENS;RAVARIAN, ROYA;GUARDIOLA, CRISTINA BORRAS;WONG, PAK MAN VICTOR |