A fusion partner comprises a choline binding domain derived from the C terminus of LytA and a chemically conjugated heterologous promiscuous T helper epitope, which can act as both an immunological partner and expression enhancer. The immunogenic composition of the fusion protein can be used for the treatment of patients suffering from or are susceptible to cancer.
申请公布号
NZ537125(A)
申请公布日期
2006.08.31
申请号
NZ20030537125
申请日期
2003.06.06
申请人
GLAXOSMITHKLINE BIOLOGICALS S
发明人
CABEZON SILVA, TERESA ELISA VIRGINIA;ELLIS, JONATHAN H;GERARD, CATHERINE MARIE GHISLAINE;HAMBLIN, PAUL A;PALMANTIER, REMI M;VINALS Y DE BASSOLS, CARLOTA