发明名称 |
BIOLOGICALLY ACTIVE COMPOUNDS AND PROCESS THEREFOR |
摘要 |
Disclosed herein are compounds of structural formula (I), and a process for making compounds of formula (I) involving selective saponification of the C-4 ester using Lewis acids such as thionyl chloride, tin (IV) chloride or hydrogen fluoride. The compounds of formula (I) are useful as cholesterol lowering agents. |
申请公布号 |
WO9409774(A1) |
申请公布日期 |
1994.05.11 |
申请号 |
WO1993US10164 |
申请日期 |
1993.10.22 |
申请人 |
MERCK & CO., INC.;CHIANG, YUAN-CHING, P.;BIFTU, TESFAYE |
发明人 |
CHIANG, YUAN-CHING, P.;BIFTU, TESFAYE |
分类号 |
C07D493/08;C07H19/01;(IPC1-7):A61K31/335;C07D319/04 |
主分类号 |
C07D493/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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