USE OF RUBESCENSINE A AND DERIVATIVES THEREOF IN PHARMACY
摘要
<p>Use of rubescensine A and derivatives thereof in pharmacy. Rubescensine A can induce the apoptosis of leukemic cells in vitro, and can prolong the survival period of mouse model of t(8;21) leukemia in vivo or delay the growth of tumor in body. Sequential, joint application of rubescensine A and chemotherapeutics, such as cytarabine or agents for inducing differentiation may be more effective in prolonging the survival period of mouse of t(8;21) leukemia.</p>
申请公布号
WO2008022505(A1)
申请公布日期
2008.02.28
申请号
WO2007CN00380
申请日期
2007.02.05
申请人
RUI JIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONGUNIVERSITY SCHOOL OF MEDICINE;CHEN, ZHU;CHEN, SAIJUAN;WANG, ZHENYI;ZHOU, GUANGBIAO