发明名称 |
ISOFORM OF THE TGF-BETA RECEPTOR II |
摘要 |
An isoform of the TGF beta receptor II comprising a sequence of about of 80 amino acids and lacking a transmembrane domain; wherein the isoform is a TGFβ-1 agonist. The isoform comprises the amino acid sequence set forth in SEQ ID No. 12. The isoform may have the amino acid sequence set forth in SEQ ID No. 2 or sequences having at least 85% sequence identity to the sequence set forth in SEQ ID No. 2. |
申请公布号 |
US2016318989(A1) |
申请公布日期 |
2016.11.03 |
申请号 |
US201415105162 |
申请日期 |
2014.12.19 |
申请人 |
CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TÉCNICAS ;FUNDACIÓN ARTICULAR ;INIS BIOTECH LLC |
发明人 |
DEWEY Ricardo Alfredo;VELASCO ZAMORA Benito Jorge;RODRÍGUEZ Tania Melina;CARREA Alejandra;CHISARI Andrea Nancy;PERONE Marcelo Javier |
分类号 |
C07K14/71;C07K16/28 |
主分类号 |
C07K14/71 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Ciudad Autónoma de Buenos Aires AR |