发明名称 Formulation of Syk inhibitors
摘要 Disclosed are pharmaceutical compositions comprising a compound having the formula:; or a pharmaceutically acceptable salt thereof, or a hydrate of thereof, and at least one pharmaceutically acceptable polymer. The pharmaceutically acceptable salt of the compound of Formula I, or a hydrate thereof, can be a mesylate salt, including, for example, a mono-mesylate or a bis-mesylate salt, or a hydrate thereof. Also disclosed are methods of use for the pharmaceutical composition.
申请公布号 US9382256(B2) 申请公布日期 2016.07.05
申请号 US201414445970 申请日期 2014.07.29
申请人 Gilead Connecticut, Inc. 发明人 Casteel Melissa Jean;Li Bei;Pakdaman Rowchanak;Sperger Diana;Stefanidis Dimitrios
分类号 A61K31/495;C07D487/04;A61K9/20;C07C309/66;A61K31/5377;A61K9/28 主分类号 A61K31/495
代理机构 代理人
主权项 1. A composition comprising: (i) a bis-mesylate salt of a compound of Formula I: or a hydrate thereof, and (ii) hydroxypropylmethylcellulose.
地址 Foster City CA US
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