发明名称 |
LIVE ATTENUATED MYCOPLASMA STRAINS |
摘要 |
<p>The present invention provides live, attenuated Mycoplasma bacteria that exhibit reduced expression of one or more proteins selected from the group consisting of pyruvate dehydrogenase, phosphopyruvate hydratase, 2-deoxyribose-5-phosphate aldolase, and ribosomal protein L35, relative to a wild-type Mycoplasma bacterium of the same species. Also provided are vaccines and vaccination methods involving the use of the live, attenuatedMycoplasma bacteria, and methods for making live attenuated Mycoplasma bacteria.</p> |
申请公布号 |
WO2009036241(A1) |
申请公布日期 |
2009.03.19 |
申请号 |
WO2008US76119 |
申请日期 |
2008.09.12 |
申请人 |
WYETH;KUMAR, MAHESH;KHAN, MUHAMMAD AYUB |
发明人 |
KUMAR, MAHESH;KHAN, MUHAMMAD AYUB |
分类号 |
A61K39/02;C12Q1/68;G01N33/569 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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