发明名称 Compounds Useful for Inhibiting Chk1
摘要 Aryl- and heteroaryl-substituted urea compounds useful in the treatment of diseases and conditions related to DNA damage or lesions in DNA replication are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating cancer and other diseases characterized by defects in DNA replication, chromosome segregation, or cell division also are disclosed.
申请公布号 US2008318974(A1) 申请公布日期 2008.12.25
申请号 US20050659389 申请日期 2005.08.18
申请人 ICOS CORPORATION 发明人 GAUDINO JOHN JOSEPH;FAROUZ FRANCINE S.;HOLCOMB RYAN COATSWORTH;THORSETT EUGENE D.
分类号 A61K31/497;A61P35/00;C07D401/04;C07D401/12 主分类号 A61K31/497
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