METHOD FOR USING PYRUVATE KINASE ACTIVATORS

摘要

PROBLEM TO BE SOLVED: To provide methods for using compounds that activate pyruvate kinase.SOLUTION: A method for increasing the lifetime of the red blood cells (RBCs) in need thereof comprises contacting blood with an effective amount of: (1) a compound disclosed herein or a pharmaceutically acceptable salt thereof; (2) a composition comprising a compound disclosed herein or a salt thereof, and a carrier; or (3) a pharmaceutical composition comprising a compound disclosed herein or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.SELECTED DRAWING: None