发明名称 |
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE |
摘要 |
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras. |
申请公布号 |
WO9410138(A1) |
申请公布日期 |
1994.05.11 |
申请号 |
WO1993US10353 |
申请日期 |
1993.10.28 |
申请人 |
MERCK & CO., INC. |
发明人 |
ANTHONY, NEVILLE, J.;DESOLMS, S., JANE;LEE, TA, J. |
分类号 |
A61K31/195;A61K31/215;A61K31/365;A61P35/00;A61P35/02;A61P43/00;C07C323/25;C07C323/52;C07C323/56;C07C323/57;C07C323/58;C07C323/59;C07D307/33;(IPC1-7):C07C323/24;A61K37/64;C07K5/00 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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